Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes

被引:0
|
作者
Venexia M. Walker
Marijana Vujkovic
Alice R. Carter
Neil M. Davies
Miriam S. Udler
Michael G. Levin
George Davey Smith
Benjamin F. Voight
Tom R. Gaunt
Scott M. Damrauer
机构
[1] MRC University of Bristol Integrative Epidemiology Unit,Bristol Medical School: Population Health Sciences
[2] University of Bristol,Department of Surgery
[3] University of Pennsylvania Perelman School of Medicine,Department of Medicine
[4] University of Pennsylvania Perelman School of Medicine,K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU
[5] Norwegian University of Science and Technology,Center for Genomic Medicine
[6] Massachusetts General Hospital,Division of Cardiovascular Medicine
[7] University of Pennsylvania Perelman School of Medicine,Department of Systems Pharmacology and Translational Therapeutics
[8] Corporal Michael Crescenz VA Medical Center,Department of Genetics
[9] University of Pennsylvania Perelman School of Medicine,Institute of Translational Medicine and Therapeutics
[10] University of Pennsylvania Perelman School of Medicine,undefined
[11] University of Pennsylvania Perelman School of Medicine,undefined
来源
Diabetologia | 2022年 / 65卷
关键词
Atherosclerotic cardiovascular disease; Coronary artery disease; Direct effect; Genome-wide association study; Indirect effect; Mediation; Mendelian randomisation; Peripheral artery disease; Type 2 diabetes;
D O I
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学科分类号
摘要
引用
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页码:790 / 799
页数:9
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