High-intensity versus low-intensity noninvasive positive pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease (HAPPEN): study protocol for a multicenter randomized controlled trial

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作者：
Zujin Luo
Chao Wu
Qi Li
Jian Zhu
Baosen Pang
Yan Shi
Yingmin Ma
Zhixin Cao
机构：
[1] Beijing Chao-Yang Hospital,Department of Respiratory and Critical Care Medicine, Beijing Engineering Research Center of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine
[2] Capital Medical University,Department of Respiratory and Critical Care Medicine
[3] People’s Hospital of Xinjiang Uygur Autonomous Region,Department of Respiratory and Critical Care Medicine, Army Institute of Respiratory Disease
[4] Chongqing Xin-Qiao Hospital,School of Automation Science and Electrical Engineering
[5] Army Military Medical University,undefined
[6] Beihang University,undefined
来源：
Trials | / 19卷
关键词：
Noninvasive positive pressure ventilation; High-intensity; Low-intensity; Chronic obstructive pulmonary disease; Exacerbation; Hypercapnia; Endotracheal intubation; Mortality;
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