Alginate-chitosan microspheres for the specific sorption of antibodies

被引：0
|
作者：
O. E. Selina
A. A. Chinarev
P. S. Obukhova
A. Bartkowiak
N. V. Bovin
E. A. Markvicheva
机构：
[1] Russian Academy of Sciences,Shemyakin
[2] University of Agriculture,Ovchinnikov Institute of Bioorganic Chemistry
来源：
Russian Journal of Bioorganic Chemistry | 2008年 / 34卷
关键词：
alginate-chitiosan microspheres; antibodies; glycoconjugates; immobilization; sorbents;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Potentially hemocompatible alginate-chitiosan microparticles and microcapsules coated with a semipermeable membrane with incorporated glycoconjugates were synthesized. The membrane acts as a barrier, which keeps the incorporated glycoconjugate from going outside but permits antibodies to penetrate inside and specifically bind to antigens, high-molecular polysaccharide conjugates. The supports obtained are highly competitive in sorption capacity with Sepharose modified by the same oligosaccharides.
引用
收藏
页码：468 / 474
页数：6
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