L-Phenylacetylcarbinol (L-PAC): biosynthesis and industrial applications

被引:0
|
作者
V.B. Shukla
P.R. Kulkarni
机构
[1] University of Mumbai,Food and Fermentation Technology Division, University Department of Chemical Technology (UDCT)
关键词
Benzaldehyde; bioreactor; biotransformation; downstream processing; L-ephedrine; free and immobilized yeast cells; L-phenylacetycarbinol; pyruvate decarboxylase;
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学科分类号
摘要
L-Phenylacetylcarbinol (L-PAC), an important drug intermediate, can be produced by biotransformation of benzaldehyde, mainly by yeast cultures but also by Zymomonas mobilis. The biotransformation by free cells, immobilized cells, mutant organisms, purified pyruvate decarboxylase as well as the use of bioreactors, the downstream processing of L-PAC and the industrial applications have been reviewed.
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页码:499 / 506
页数:7
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