At a Glance: An Update on Neuroimaging and Retinal Imaging in Alzheimer’s Disease and Related Research

Neuroimaging serves a variety of purposes in Alzheimer’s disease (AD) and related dementias (ADRD) research — from measuring microscale neural activity at the subcellular level, to broad topological patterns seen across macroscale-brain networks, and everything in between. In vivo imaging provides insight into the brain’s structure, function, and molecular architecture across numerous scales of resolution; allowing examination of the morphological, functional, and pathological changes that occurs in patients across different AD stages (1). AD is a complex and potentially heterogenous disease, with no proven cure and no single risk factor to isolate and measure, whilst known risk factors do not fully account for the risk of developing this disease (2).