Whole-brain radiation therapy in breast cancer patients with brain metastases

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作者
Cyrus Chargari
François Campana
Jean-Yves Pierga
Lionel Védrine
Damien Ricard
Sylvestre Le Moulec
Alain Fourquet
Youlia M. Kirova
机构
[1] Medical and Radiation Oncology Unit Hôpital d'Instruction des Armées du Val-de-Grâce,Department of Medical Oncology
[2] Neurology Unit Hôpital d'Instruction des Armées du Val-de-Grâce,Department of Radiation Oncology
[3] Institut Curie,undefined
[4] Institut Curie,undefined
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摘要
Brain metastases are a frequent complication in patients with advanced breast cancer. Whole-brain radiation therapy (WBRT) is the standard treatment for these patients, but it can cause neurocognitive damage, and results are suboptimal. Therapies that reduce toxic effects, improve local control, and prevent recurrences are needed. The authors of this Review outline the current strategies and novel developments in WBRT, and discuss new irradiation modalities that are improving outcomes in breast cancer patients with brain metastases.
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页码:632 / 640
页数:8
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