The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison

被引:0
|
作者
Theresa M. Ballard
Marie L. Woolley
Eric Prinssen
Jörg Huwyler
Richard Porter
Will Spooren
机构
[1] F. Hoffmann-La Roche Ltd.,PRBD
[2] GlaxoSmithKline plc,N, Neuroscience Research
[3] F. Hoffmann-La Roche,Psychiatry CEDD
来源
Psychopharmacology | 2005年 / 179卷
关键词
MPEP; mGlu5 receptor antagonist; Anxiety; Cognition; Conflict task; Conditioned emotional response; Delayed match to position; Water maze; Rat;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:218 / 229
页数:11
相关论文
共 50 条
  • [1] The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison
    Ballard, TM
    Woolley, ML
    Prinssen, E
    Huwyler, J
    Porter, R
    Spooren, W
    [J]. PSYCHOPHARMACOLOGY, 2005, 179 (01) : 218 - 229
  • [2] MPEP, mGLU5 receptor antagonist, regulates NPYmRNA expression in hippocampal and amygdalar neurons
    Smialowska, M
    Wieronska, JM
    Branski, P
    Obuchowicz, E
    Pilc, A
    [J]. POLISH JOURNAL OF PHARMACOLOGY, 2004, 56 (06): : 709 - 718
  • [3] Effects of selective glutamate mGlu5 receptor antagonist, MPEP, on sleep and wakefulness in the rat
    Scesa, G. L.
    Cavas, M.
    Navarro, J. F.
    [J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2010, 20 : S239 - S239
  • [4] Anxiolytic-like effects of the selective mGlu5 receptor antagonist MPEP in punished responding
    Spooren, W
    Vivian, J
    Ballard, TF
    [J]. NEUROPHARMACOLOGY, 2002, 43 (02) : 309 - 310
  • [5] Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats
    Wieronska, JM
    Szewczyk, B
    Branski, P
    Palucha, A
    Pilc, A
    [J]. AMINO ACIDS, 2002, 23 (1-3) : 213 - 216
  • [6] Potential anti-addictive effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist
    Palucha, A
    Branski, P
    Szewczyk, B
    Wieronska, JM
    Tokarski, K
    Pilc, A
    [J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2002, 12 : S390 - S390
  • [7] Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats
    J. M. Wieronska
    B. Szewczyk
    P. Branski
    A. Palucha
    A. Pilc
    [J]. Amino Acids, 2002, 23 : 213 - 216
  • [8] Effects of MGLU5 receptor antagonists MTEP and MPEP on contextual fear conditioning
    Imre, G.
    Gyertyan, I.
    [J]. BEHAVIOURAL PHARMACOLOGY, 2007, 18 : S76 - S77
  • [9] Effect of mGlu5 antagonist, 2-methyl-6-(phenylethynyl)pyridine (MPEP) on kindled seizures in the rat
    Keaney, KJ
    Chapman, AG
    Meldrum, BS
    [J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2000, 12 : 37 - 37
  • [10] Glutamate mGlu5 receptor antagonist, MPEP, reduces the quinpirole-induced compulsive-like checking in rats
    Gok, Sule
    Demet, Mehmet Murat
    Ozturk, Zeynep
    [J]. JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS, 2017, 15 : 13 - 18