Are anti-cyclic citrullinated peptide antibodies pathogenic in rheumatoid arthritis?

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V Michael Holers
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[1] the Head of the Division of Rheumatology at the University of Colorado Health Sciences Center in Denver,
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New insights into the etiology of rheumatoid arthritis have suggested that humoral autoimmunity might have a substantive, possibly even causal role in the pathogenesis of disease. In this Viewpoint, Dr Holers will discuss the basis of this hypothesis, focusing on the role of anti-cyclic citrullinated peptide antibodies.
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页码:400 / 401
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