Association of the human bradykinin B2 receptor gene with chronic renal failure

被引：0
|
作者：
Lucyna Jozwiak
Andrzej Drop
Kinga Buraczynska
Piotr Ksiazek
Piotr Mierzicki
Monika Buraczynska
机构：
[1] Skubiszewski Medical University,Laboratory for Molecular Diagnostics of Multifactorial Diseases, Department of Nephrology
[2] Skubiszewski Medical University,Department of Radiology
来源：
Molecular Diagnosis | 2004年 / 8卷 / 3期
关键词：
Chronic Renal Failure; Bradykinin; Polycystic Kidney Disease; ESRD Patient; Interstitial Nephritis;
D O I：
10.1007/BF03260059
中图分类号：
学科分类号：
摘要：
Introduction: The kallikrein-kinin system plays an important role in blood pressure homeostasis and renal sodium regulation, and some studies have reported that the kinins have a protective effect against hypertension and the development of renal disease. The B2-bradykinin receptor (B2R) mediates the majority of physiological actions of bradykinin. We investigated the effect of the C181→T polymorphism in exon 2 of the B2R gene in patients with end-stage renal disease (ESRD).
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页码：157 / 161
页数：4
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