Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication

被引:0
|
作者
G. M. Allan
F. McNeilly
J. Ellis
S. Krakowka
B. Meehan
I. McNair
I. Walker
S. Kennedy
机构
[1] Virology Department,
[2] Veterinary Sciences Division,undefined
[3] Department of Agriculture and Rural Development for N. Ireland,undefined
[4] Belfast,undefined
[5] Northern Ireland,undefined
[6] Department of Veterinary Microbiology and Pathology,undefined
[7] Western College of Veterinary Medicine,undefined
[8] University of Saskatchewan,undefined
[9] Saskatoon,undefined
[10] Canada,undefined
[11] Department of Veterinary Biosciences,undefined
[12] College of Veterinary Medicine,undefined
[13] The Ohio State University,undefined
[14] Columbus,undefined
[15] Ohio,undefined
[16] U.S.A.,undefined
来源
Archives of Virology | 2000年 / 145卷
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摘要
 Experimental infection of colostrum-deprived (CD) pigs with a combined inoculum of porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiated the replication and distribution of PCV2 virus, when compared with pigs inoculated with PCV2 alone. The replication and distribution of PRRSV in dually infected pigs was not enhanced, when compared to pigs inoculated with PRRSV alone. The mechanisms involved in the potentiation of PCV2 replication in PCV2/PRRSV and PCV2/porcine parvovirus (PPV) dually infected pigs may relate to the fact that monocyte/macrophage cell types are common targets of these 3 viruses.
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页码:2421 / 2429
页数:8
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