Gene prediction: compare and CONTRAST

被引:0
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作者
Paul Flicek
机构
[1] European Bioinformatics Institute,
[2] Wellcome Trust Genome Campus,undefined
来源
关键词
Multiple Sequence Alignment; Gene Prediction; Prediction Program; Conditional Random Field; Generalize Hide Markov Model;
D O I
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学科分类号
摘要
CONTRAST, a new gene-prediction algorithm that uses sophisticated machine-learning techniques, has pushed de novo prediction accuracy to new heights, and has significantly closed the gap between de novo and evidence-based methods for human genome annotation.
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