A Charge Variant of Bevacizumab Offers Enhanced FcRn-Dependent Pharmacokinetic Half-Life and Efficacy

被引：0
|
作者：
Sumit K. Singh
Deepak Kumar
Saurabh Nagpal
Sunil K. Dubey
Anurag S. Rathore
机构：
[1] IIT(BHU),School of Biochemical Engineering
[2] Indian Institute of Technology,Department of Chemical Engineering, IIT, DBT Center of Excellence for Biopharmaceutical Technology
[3] Agilent Technologies,undefined
[4] R&D Healthcare Division,undefined
[5] Emami Limited,undefined
来源：
Pharmaceutical Research | 2022年 / 39卷
关键词：
bevacizumab; FcRn mediated half-life extension; mAb lysine variants; pharmacokinetics; proteomics;
D O I：
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摘要：
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页码：851 / 865
页数：14
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