Mapping of rat Chromosome 2 markers generated from chromosome-sorted DNA

被引：0
|
作者：
Alan Y. Deng
Clara M. Jackson
Barbara Hoebee
John P. Rapp
机构：
[1] Department of Physiology and Molecular Medicine,
[2] Medical College of Ohio,undefined
[3] 3000 Arlington Avenue,undefined
[4] P.O. Box 10008,undefined
[5] Toledo,undefined
[6] Ohio 43699-0008,undefined
[7] USA,undefined
[8] Department of Medicine,undefined
[9] Medical College of Ohio,undefined
[10] Toledo,undefined
[11] Ohio 43699,undefined
[12] USA,undefined
[13] Laboratory of Health Effects Research,undefined
[14] National Institutes of Public Health and Environmental Protection,undefined
[15] Bilthoven 3720 RA,undefined
[16] The Netherlands,undefined
来源：
Mammalian Genome | 1997年 / 8卷
关键词：
Blood Pressure; Quantitative Trait Locus; Quantitative Trait; Current Work; Fine Mapping;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A quantitative trait locus (QTL) for blood pressure has recently been mapped to a region of roughly 30 cM on rat Chromosome (Chr) 2 by linkage and by the use of congenic strains. For further fine mapping of the QTL, however, closely linked chromosome markers residing in this 30-cM region are required. In the current work, 36 new markers were generated by screening rat Chr 2-sorted DNA libraries and subsequently mapped using five F2 populations. Combining new and existing markers, the marker density for the 30-cM region approaches, on average, one marker per 1.1 cM.
引用
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页码：731 / 735
页数：4
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