Immune checkpoint blockade therapy of mesothelioma: a clinical and radiological challenge

被引：0
|
作者：
Luana Calabrò
Aldo Morra
Robin Cornelissen
Joachim Aerts
Michele Maio
机构：
[1] University Hospital of Siena,Medical Oncology and Immunotherapy, Center for Immuno
[2] Istituto Toscano Tumori,Oncology
[3] Siena,Department of Radiology
[4] Euganea Medica Diagnostic Center,undefined
[5] Erasmus MC Cancer Institute,undefined
来源：
Cancer Immunology, Immunotherapy | 2018年 / 67卷
关键词：
Mesothelioma; Immune checkpoint; Immunotherapy; NIBIT-2016;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Treatment of malignant pleural mesothelioma (MPM) represents a highly unmet medical need. Here, we discuss the results and therapeutic potential of first- and second-generation immunomodulatory antibodies targeting distinct immune checkpoints for the treatment of MPM, as well as their prospective therapeutic role in combination strategies. We also discuss the role of appropriate radiological criteria of response for MPM and the potential need of ad hoc criteria of disease evaluation in MPM patients undergoing treatment with immunotherapeutic agents.
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页码：1317 / 1324
页数：7
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