Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway

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作者
Bo Ma
Qi Zhang
Di Wu
Yong-lu Wang
Ying-ying Hu
Yan-ping Cheng
Zhen-dong Yang
Ya-ya Zheng
Han-Jie Ying
机构
[1] School of Pharmaceutical Sciences,Division of Clinical Pharmacology and Therapeutics
[2] Nanjing University of Technology,undefined
[3] Jiangsu Provincial Institute of Material Medica,undefined
[4] Nanjing University of Technology,undefined
[5] Laboratory for Applied PK/PD,undefined
[6] The Children's Hospital of Philadelphia,undefined
[7] Kinetic Modeling and Simulation Core,undefined
[8] Institute of Translational Medicine and Therapeutics,undefined
[9] University of Pennsylvania,undefined
[10] School of Life Science & Pharmaceutical Engineering,undefined
[11] Nanjing University of Technology,undefined
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关键词
osteoporosis; ovariectomy; strontium fructose 1,6-diphosphate; strontium ranelate; osteoprotegerin (OPG); receptor activator of NF-κB ligand (RANKL); bone mineral density; tartrate-resistant acid phosphatase 5 (TRACP5); N-telopeptide of type I collagen (NTx);
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页码:479 / 489
页数:10
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