An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression

被引：0
|
作者：
Yufeng Qin
John D. Roberts
Sara A. Grimm
Fred B. Lih
Leesa J. Deterding
Ruifang Li
Kaliopi Chrysovergis
Paul A. Wade
机构：
[1] Eukaryotic Transcriptional Regulation Group,
[2] Epigenetics and Stem Cell Biology Laboratory,undefined
[3] National Institute of Environmental Health Sciences,undefined
[4] Integrative Bioinformatics Group,undefined
[5] Epigenetics and Stem Cell Biology Laboratory,undefined
[6] National Institute of Environmental Health Sciences,undefined
[7] Mass Spectrometry Research & Support Group,undefined
[8] Epigenetics and Stem Cell Biology Laboratory,undefined
[9] National Institute of Environmental Health Sciences,undefined
来源：
Genome Biology | / 19卷
关键词：
Microbiome; Obesity; Cancer; Colorectal cancer; Epigenetics; Transcription factor; Gene expression; Histone methylation; Histone acetylation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression
    Qin, Yufeng
    Roberts, John D.
    Grimm, Sara A.
    Lih, Fred B.
    Deterding, Leesa J.
    Li, Ruifang
    Chrysovergis, Kaliopi
    Wade, Paul A.
    GENOME BIOLOGY, 2018, 19
  • [2] An obesity-associated gut microbiome with increased capacity for energy harvest
    Peter J. Turnbaugh
    Ruth E. Ley
    Michael A. Mahowald
    Vincent Magrini
    Elaine R. Mardis
    Jeffrey I. Gordon
    Nature, 2006, 444 : 1027 - 1031
  • [3] An obesity-associated gut microbiome with increased capacity for energy harvest
    Turnbaugh, Peter J.
    Ley, Ruth E.
    Mahowald, Michael A.
    Magrini, Vincent
    Mardis, Elaine R.
    Gordon, Jeffrey I.
    NATURE, 2006, 444 (7122) : 1027 - 1031
  • [4] Protective Effects of Anthocyanins in Obesity-Associated Inflammation and Changes in Gut Microbiome
    Jayarathne, Shasika
    Stull, April J.
    Park, Oak-Hee
    Kim, Jung Han
    Thompson, Leslie
    Moustaid-Moussa, Naima
    MOLECULAR NUTRITION & FOOD RESEARCH, 2019, 63 (20)
  • [5] Diet, inflammation and the gut microbiome: Mechanisms for obesity-associated cognitive impairment
    Leigh, Sarah-Jane
    Morris, Margaret J.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2020, 1866 (06):
  • [6] Apigenin Alleviates Obesity-Associated Metabolic Syndrome by Regulating the Composition of the Gut Microbiome
    Qiao, Yuan
    Zhang, Zhichun
    Zhai, Yuanyuan
    Yan, Xu
    Zhou, Wenling
    Liu, Hao
    Guan, Lingling
    Peng, Liang
    FRONTIERS IN MICROBIOLOGY, 2022, 12
  • [7] Does Gut-Microbiome Interaction Protect against Obesity and Obesity-Associated Metabolic Disorders?
    Zawada, Agnieszka
    Rychter, Anna Maria
    Ratajczak, Alicja Ewa
    Lisiecka-Masian, Agata
    Dobrowolska, Agnieszka
    Krela-Kazmierczak, Iwona
    MICROORGANISMS, 2021, 9 (01) : 1 - 19
  • [8] Altered intestinal neuroendocrine gene expression in humans with obesity
    Ritze, Yvonne
    Hengelhaupt, Christina
    Bardos, Gyoengyi
    Ernst, Barbara
    Thurnheer, Martin
    D'Haese, Jan G.
    Bischoff, Stephan C.
    Schultes, Bernd
    OBESITY, 2015, 23 (11) : 2278 - 2285
  • [9] Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives
    Vallianou, Natalia
    Stratigou, Theodora
    Christodoulatos, Gerasimos Socrates
    Dalamaga, Maria
    CURRENT OBESITY REPORTS, 2019, 8 (03) : 317 - 332
  • [10] Sex differences in colonic gene expression and fecal microbiota composition in a mouse model of obesity-associated colorectal cancer
    Yoo-Mee Chang
    Yoo-Ree Kang
    Yu-Gyeong Lee
    Mi-Kyung Sung
    Scientific Reports, 14
12345