Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

被引：0
|
作者：
Barbara Rehermann
机构：
[1] Immunology Section,Department of Health and Human Services
[2] Liver Diseases Branch,undefined
[3] National Institute of Diabetes and Digestive and Kidney Diseases,undefined
[4] US National Institutes of Health,undefined
来源：
Nature Medicine | 2013年 / 19卷
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摘要：
During chronic infection caused by hepatitis C and B viruses, effector adaptive immune cells are exhausted and incapable of clearing the virus, but they can still contribute to liver inflammation in this setting. This Review discusses the regulatory role of nonspecific immune natural killer (NK) cells, which, along with other immune regulatory signals, help the host counteract liver disease progression and immunopathology by controlling virus-specific immunity.
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页码：859 / 868
页数：9
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