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Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Canc Hosp, Dept Colorectal Surg,Natl Canc Ctr, 17 Panjiayuan South Lane, Beijing 100021, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Canc Hosp, Dept Colorectal Surg,Natl Canc Ctr, 17 Panjiayuan South Lane, Beijing 100021, Peoples R China