Baculovirus as versatile vectors for protein expression in insect and mammalian cells

被引：0
|
作者：
Thomas A Kost
J Patrick Condreay
Donald L Jarvis
机构：
[1] Gene Expression Protein Biochemistry,Department of Molecular Biology
[2] GlaxoSmithKline R&D,undefined
[3] University of Wyoming,undefined
来源：
Nature Biotechnology | 2005年 / 23卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Today, many thousands of recombinant proteins, ranging from cytosolic enzymes to membrane-bound proteins, have been successfully produced in baculovirus-infected insect cells. Yet, in addition to its value in producing recombinant proteins in insect cells and larvae, this viral vector system continues to evolve in new and unexpected ways. This is exemplified by the development of engineered insect cell lines to mimic mammalian cell glycosylation of expressed proteins, baculovirus display strategies and the application of the virus as a mammalian-cell gene delivery vector. Novel vector design and cell engineering approaches will serve to further enhance the value of baculovirus technology.
引用
收藏
页码：567 / 575
页数：8
相关论文
共 50 条
  • [1] Baculovirus as versatile vectors for protein expression in insect and mammalian cells
    Kost, TA
    Condreay, JP
    Jarvis, DL
    [J]. NATURE BIOTECHNOLOGY, 2005, 23 (05) : 567 - 575
  • [2] Baculovirus expression vectors for insect and mammalian cells
    Condreay, J. Patrick
    Kost, Thomas. A.
    [J]. CURRENT DRUG TARGETS, 2007, 8 (10) : 1126 - 1131
  • [3] Baculovirus vectors for expression in insect cells
    Jones, I
    Morikawa, Y
    [J]. CURRENT OPINION IN BIOTECHNOLOGY, 1996, 7 (05) : 512 - 516
  • [4] A baculovirus expression vector system for simultaneous protein expression in insect and mammalian cells
    Philipps, B
    Forstner, M
    Mayr, LM
    [J]. BIOTECHNOLOGY PROGRESS, 2005, 21 (03) : 708 - 711
  • [5] Baculovirus expression vectors - Producing proteins with insect cells
    Schneider, I
    [J]. GENETIC ENGINEERING NEWS, 1999, 19 (03): : 8 - +
  • [6] Expression of neuroparsin cDNA in insect cells using Baculovirus vectors
    Girardie, J
    Chaabihi, H
    Fournier, B
    Lagueux, M
    Girardie, A
    [J]. ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 2001, 46 (1-2) : 26 - 35
  • [7] Expression of neuroparsin cDNA in insect cells using baculovirus vectors
    Girardie, J
    Chaabihi, H
    Fournier, B
    Lagueux, M
    Girardie, A
    [J]. ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 1997, 36 (01) : 11 - 23
  • [8] Baculovirus vectors for efficient gene delivery and expression in mammalian cells
    Koroleva, N. N.
    Spirin, P. V.
    Timokhova, A. V.
    Rubtzov, P. M.
    Kochetkov, S. N.
    Prasolov, V. S.
    Beljelarskaya, S. N.
    [J]. MOLECULAR BIOLOGY, 2010, 44 (03) : 479 - 487
  • [9] Baculovirus vectors for efficient gene delivery and expression in mammalian cells
    N. N. Koroleva
    P. V. Spirin
    A. V. Timokhova
    P. M. Rubtzov
    S. N. Kochetkov
    V. S. Prasolov
    S. N. Beljelarskaya
    [J]. Molecular Biology, 2010, 44 : 479 - 487
  • [10] Baculovirus as a highly efficient expression vector in insect and mammalian cells
    Hu, YC
    [J]. ACTA PHARMACOLOGICA SINICA, 2005, 26 (04) : 405 - 416
12345