Genome-wide polygenic risk predictors for kidney disease

被引：0
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作者：
Lili Liu
Krzysztof Kiryluk
机构：
[1] Columbia University,Department of Medicine, Division of Nephrology, College of Physicians & Surgeons
来源：
Nature Reviews Nephrology | 2018年 / 14卷
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摘要：
A new study reports that genome-wide polygenic risk scores can identify individuals at risk of common complex diseases, such as coronary artery disease or type 2 diabetes, with comparable performance to that of monogenic mutation screens. These findings support the potential clinical utility of genome-wide association study (GWAS)-based risk stratification; however, several issues need to be addressed before this approach can be applied to kidney disease.
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页码：723 / 724
页数：1
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