How can we get more beta cells?

被引：8

作者：

Inada A. ^{[1
]}

Bonner-Weir S. ^{[1
]}

Toschi E. ^{[1
]}

机构：

[1] Joslin Diabetes Center, Boston, MA 02215, One Joslin Place

来源：

Current Diabetes Reports | 2006年 / 6卷 / 2期

关键词：

Beta Cell; Hepatocyte Growth Factor; Acinar Cell; Human Islet; Protein Transduction Domain;

D O I：

10.1007/s11892-006-0018-7

中图分类号：

学科分类号：

摘要：

The need for a reliable source of functional β cells has led to many new investigations in an effort to drive the differentiation of embryonic stem cells, of putative stem cells, or of pancreatic progenitor cells to form new β cells. There appears to be a plasticity of pancreatic cells in vitro that may be exploited to generate the necessary β cells. Major questions still remain: whether there are true pancreatic stem cells, what are the pancreatic progenitor cells after birth, and whether expanded β cells themselves could serve as the source. Copyright © 2006 by Current Science Inc.

引用

页码：96 / 101

页数：5

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