Urease inhibition of oxovanadium(V) complexes with hydrazone and hydroxamate ligands

Two new oxovanadium(V) complexes, [VOL1(SHA)] (I) and [VOL2(BHA)] (II), were prepared by the reaction of [VO(Acac)2] (Acac = acetylacetonate) with N′-(2-hydroxybenzylidene)isonicotinohydrazide (H2L1) and salicylhydroxamic acid (HSHA) and 4-chloro-N′-(2-hydroxy-3-methoxybenzylidene)benzohydrazide (H2L2) and benzohydroxamic acid (HBHA), respectively, in methanol. Crystal and molecular structures of the complexes were determined by elemental analysis, infrared spectra and single crystal X-ray diffraction (CIF file CCDC nos. 978238 (I) and 978392 (II)). The V atoms are in octahedral coordination. Thermal stability and the inhibition of urease of the complexes were studied.