Cytomegalovirus (CMV) retinitis in AIDS: ganciclovir implant in comparison to systemic therapyGanciclovir-Implantat im Vergleich zur systemischen Therapie
Key words Sustained-release ganciclovir • Cytomegalovirus retinitis • AIDS • Ganciclovir implant • Ganciclovir intraocular device;
Schlüsselwörter Zytomegalievirus-Retinitis • Lokaltherapie • AIDS • Ganciclovirimplantat • Ganciclovirpellet;
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Introduction: Untreated CMV retinitis with AIDS leads to blindness; therefore, a life-long virostatic treatment is required. It can either be administered systemically or locally, as there are different advantages and disadvantages. When treating patients we aim at therapy that preserves vision without diminishing quality of life. It should induce as few drug-induced side effects as possible and not shorten the patient's life expectation.