Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK

被引：0
|
作者：
Fangzhou Guo
Guoyuan Ling
Jianting Qiu
Jicheng Li
Yu Gan
YingYing Yu
Jiamei Tang
Ligen Mo
Haozhe Piao
机构：
[1] Guangxi Medical University Cancer Hospital,Department of Neurosurgery
[2] Dalian Medical University,Graduate School
[3] Cancer Hospital of Dalian University of Technology,Department of Neurosurgery, Cancer Hospital of China Medical University
[4] China Medical University,Graduate School
[5] Liaoning University of Traditional Chinese Medicine,Graduate School
来源：
Chinese Medicine | / 19卷
关键词：
Juglone; Glioblastoma; Ferroptosis; p38MAPK; Nrf2;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
    Guo, Fangzhou
    Ling, Guoyuan
    Qiu, Jianting
    Li, Jicheng
    Gan, Yu
    Yu, YingYing
    Tang, Jiamei
    Mo, Ligen
    Piao, Haozhe
    CHINESE MEDICINE, 2024, 19 (01)
  • [2] Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD
    Zhang, Zixiao
    Fu, Congli
    Liu, Jiaxin
    Sai, Xiaoyan
    Qin, Chu
    Di, Tingting
    Yang, Yue
    Wu, Yan
    Bian, Tao
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2021, 16 : 3347 - 3362
  • [3] Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis
    Liu, Xing
    Peng, Xinhui
    Cen, Shuai
    Yang, Cuiting
    Ma, Zhijie
    Shi, Xinyuan
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [4] Britanin alleviates chondrocyte ferroptosis in osteoarthritis by regulating the Nrf2-GPX4 axis
    Xiong, Chenwei
    Shang, Jingjing
    Yu, Zhentang
    Zhang, Junjie
    Miao, Kaisong
    Yu, Changlin
    Huang, Yong
    Weng, Yiping
    Zhou, Xindie
    ARABIAN JOURNAL OF CHEMISTRY, 2024, 17 (09)
  • [5] EGCG Alleviates DSS-Induced Colitis by Inhibiting Ferroptosis Through the Activation of the Nrf2-GPX4 Pathway and Enhancing Iron Metabolism
    Chen, Junzhou
    Yin, Conghui
    Zhang, Yilong
    Lai, Xin
    Liu, Chen
    Luo, Yuheng
    Luo, Junqiu
    He, Jun
    Yu, Bing
    Wang, Quyuan
    Wang, Huifen
    Chen, Daiwen
    Wu, Aimin
    NUTRIENTS, 2025, 17 (03)
  • [6] Methylseleninic Acid Elevating the Nrf2-GPX4 Axis Relieves Endothelial Dysfunction and Ferroptosis Induced by Arsenic Exposure
    Cai, Zhihui
    Zhang, Yutian
    He, Leting
    Cui, Miao
    Zhang, Weijie
    Lingling, E.
    Yang, Hui
    Ling, Qinjie
    Hoffmann, Peter R.
    He, Jingjun
    Gou, Shan
    Liu, Fei
    Huang, Zhi
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 73 (12) : 7445 - 7455
  • [7] Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/ GPX4 regulatory axis
    Wen, Rui-jia
    Dong, Xin
    Zhuang, Hao-wen
    Pang, Feng-xiang
    Ding, Shou-chang
    Li, Nan
    Mai, Yong-xin
    Zhou, Shu-ting
    Wang, Jun-yan
    Zhang, Jin-fang
    PHYTOMEDICINE, 2023, 116
  • [8] Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis
    Huang, Rui
    Chu, Dawei
    Shi, Jiandang
    Xu, Ruiqing
    Wang, Kun
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [9] Dictamnine alleviates DSS-induced colitis mice by inhibiting ferroptosis of enterocytes via activating Nrf2-Gpx4 signaling pathway
    Yuan, Jin
    Su, Junwei
    Zhong, Shaowen
    Yuan, Xin
    Zhu, Jianping
    Lu, Shuangxi
    Zhang, Di
    Li, Guiling
    Xue, Hanyu
    Yan, Min
    Yue, Lei
    Zhang, Tianwu
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2025, 997
  • [10] Arctigenin induces apoptosis in colon cancer cells through ROS/p38MAPK pathway
    Li, Qing-chun
    Liang, Yun
    Tian, Yuan
    Hu, Guang-rui
    JOURNAL OF BUON, 2016, 21 (01): : 87 - 94
12345