Epigenetic programming and reprogramming during development

被引：0
|
作者：
Irene Cantone
Amanda G Fisher
机构：
[1] Lymphocyte Development Group,
[2] Medical Research Council Clinical Sciences Centre,undefined
[3] Imperial College London,undefined
[4] Hammersmith Hospital Campus,undefined
来源：
Nature Structural & Molecular Biology | 2013年 / 20卷
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摘要：
Global erasure and re-establishment of chromatin-based and DNA-based epigenetic marks occurs naturally in the mammalian life cycle, but it can also be artificially engineered using various reprogramming strategies. In this Review, recent advances in understanding how epigenetic remodeling contributes to cell-fate reprogramming in vivo and in vitro are summarized.
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页码：282 / 289
页数：7
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