CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling

被引:0
|
作者
Qian Zhong
Yuxin Fang
Qiuhua Lai
Shanci Wang
Chengcheng He
Aimin Li
Side Liu
Qun Yan
机构
[1] Southern Medical University,Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital
关键词
Colorectal cancer; CPEB3; Cytoplasmic polyadenylation element binding protein 3; Tumor-associated macrophage; IL-6; EMT;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling
    Zhong, Qian
    Fang, Yuxin
    Lai, Qiuhua
    Wang, Shanci
    He, Chengcheng
    Li, Aimin
    Liu, Side
    Yan, Qun
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 39 (01)
  • [2] CPEB3 functions as a tumor suppressor in colorectal cancer via JAK/STAT signaling
    Fang, Yuxin
    Zhong, Qian
    Wang, Yadong
    Gu, Chuncai
    Liu, Side
    Li, Aimin
    Yan, Qun
    AGING-US, 2020, 12 (21): : 21404 - 21422
  • [3] Resolvin D1 Inhibits IL-6-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Targeting IL-6/STAT3 Signaling
    Du, Heng
    You, Lijuan
    Wu, Anding
    Wang, Fei
    Yu, Jie
    Chen, Chaowu
    CELL BIOCHEMISTRY AND BIOPHYSICS, 2024, 82 (02) : 1453 - 1461
  • [4] HBD Inhibits the Development of Colitis-Associated Cancer in Mice via the IL-6R/STAT3 Signaling Pathway
    Deng, Song
    Wang, Aiping
    Chen, Xi
    Du, Qun
    Wu, Yanli
    Chen, Gang
    Guo, Wenfeng
    Li, Yanwu
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (05)
  • [5] Targeting crosstalk of STAT3 between tumor-associated M2 macrophages and Tregs in colorectal cancer
    Huang, Lili
    Zhao, Yu
    Shan, Mengying
    Wang, Sitong
    Chen, Jianhua
    Liu, Zhuqing
    Xu, Qing
    CANCER BIOLOGY & THERAPY, 2023, 24 (01)
  • [6] IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer
    Bak, Yesol
    Kwon, Taeho
    Bak, In Seon
    Hong, Jintae
    Yu, Dae-Yeul
    Yoon, Do-Young
    ONCOTARGET, 2016, 7 (06) : 7307 - 7317
  • [7] Tumor-associated macrophages induce epithelial-mesenchymal transition and promote lung metastasis in breast cancer by activating the IL-6/STAT3/ TGM2 axis
    Qi, Yana
    Li, Ranran
    Han, Mingyong
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 143
  • [8] M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway
    Rong-Rong Yao
    Jing-Huan Li
    Rui Zhang
    Rong-Xin Chen
    Yan-Hong Wang
    World Journal of Surgical Oncology, 16
  • [9] M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway
    Yao, Rong-Rong
    Li, Jing-Huan
    Zhang, Rui
    Chen, Rong-Xin
    Wang, Yan-Hong
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2018, 16
  • [10] Quercetin inhibits epithelial-mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial-mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells
    Yu, Dinglai
    Ye, Tingting
    Xiang, Yukai
    Shi, Zhehao
    Zhang, Jie
    Lou, Bin
    Zhang, Fan
    Chen, Bicheng
    Zhou, Mengtao
    ONCOTARGETS AND THERAPY, 2017, 10 : 4719 - 4729