Roles for noncoding RNAs in cell-fate determination and regeneration

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作者
Mo Li
Juan Carlos Izpisua Belmonte
机构
[1] Mo Li and Juan Carlos Izpisua Belmonte are at the Gene Expression Laboratory,
[2] Salk Institute for Biological Studies,undefined
[3] La Jolla,undefined
[4] California,undefined
[5] USA.,undefined
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摘要
Cellular fate is determined by transcriptional networks and epigenetic states. In addition to protein factors, noncoding RNAs (ncRNAs), particularly microRNAs and long ncRNAs, are able to remodel transcriptional circuits and reshape epigenetic landscapes. This Commentary highlights the emerging roles of these ncRNAs in cellular reprogramming, transdifferentiation and organ regeneration.
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页码:2 / 4
页数:2
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