Proteomics analysis of prefrontal cortex of Alzheimer’s disease patients revealed dysregulated proteins in the disease and novel proteins associated with amyloid-β pathology

被引:0
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作者
Ana Montero-Calle
Raquel Coronel
María Garranzo-Asensio
Guillermo Solís-Fernández
Alberto Rábano
Vivian de los Ríos
María Jesús Fernández-Aceñero
Marta L. Mendes
Javier Martínez-Useros
Diego Megías
María Teresa Moreno-Casbas
Alberto Peláez-García
Isabel Liste
Rodrigo Barderas
机构
[1] Instituto de Salud Carlos III,Functional Proteomics Unit, Chronic Disease Programme (UFIEC)
[2] Unidad de Regeneración Neural,Molecular Imaging and Photonics Division, Chemistry Department, Faculty of Sciences
[3] Unidad Funcional de Investigación de Enfermedades Crónicas,Alzheimer Disease Research Unit
[4] Instituto de Salud Carlos III (ISCIII),Surgical Pathology Department
[5] KU Leuven,Department of Infection and Immunity
[6] CIEN Foundation,Translational Oncology Division, OncoHealth Institute
[7] Queen Sofia Foundation Alzheimer Center,Advanced Optical Microscopy Unit, UCCTs
[8] Centro de Investigaciones Biológicas,Molecular Pathology and Therapeutic Targets Group
[9] CSIC,Area of Physiology, Department of Basic Health Sciences, Faculty of Health Sciences
[10] Hospital Universitario Clínico San Carlos,undefined
[11] Luxembourg Institute of Health,undefined
[12] Health Research Institute-University Hospital Fundación Jiménez Díaz-Universidad Autónoma de Madrid,undefined
[13] Instituto de Salud Carlos III (ISCIII),undefined
[14] Investén-isciii,undefined
[15] Instituto de Salud Carlos III,undefined
[16] CIBERFES,undefined
[17] La Paz University Hospital (IdiPAZ),undefined
[18] Rey Juan Carlos University,undefined
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关键词
Alzheimer’s disease; Quantitative proteomics; 10-plex TMT; Neurodegeneration; Biomarkers; Amyloid-β interactors; Liquid biopsy;
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