Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine

被引：0
|
作者：
Daniel C. Moreira
Sujatha Venkataraman
Apurva Subramanian
John Desisto
Ilango Balakrishnan
Eric Prince
Angela Pierce
Andrea Griesinger
Adam Green
Charles G. Eberhardt
Nicholas K. Foreman
Rajeev Vibhakar
机构：
[1] University of Colorado Anschutz Medical Campus,Department of Pediatrics
[2] Children’s Hospital Colorado,Morgan Adams Foundation Pediatric Brain Tumor Research Program
[3] University of Colorado Denver,Department of Neurosurgery
[4] Johns Hopkins University,Department of Pathology, School of Medicine
[5] St. Jude Children’s Research Hospital,Department of Oncology
来源：
Journal of Neuro-Oncology | 2020年 / 147卷
关键词：
MYC; Replication stress; Medulloblastoma; AZD1775; Gemcitabine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：531 / 545
页数：14
相关论文
共 50 条
  • [1] Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine
    Moreira, Daniel C.
    Venkataraman, Sujatha
    Subramanian, Apurva
    Desisto, John
    Balakrishnan, Ilango
    Prince, Eric
    Pierce, Angela
    Griesinger, Andrea
    Green, Adam
    Eberhardt, Charles G.
    Foreman, Nicholas K.
    Vibhakar, Rajeev
    JOURNAL OF NEURO-ONCOLOGY, 2020, 147 (03) : 531 - 545
  • [2] TARGETING APOPTOSIS AS A NOVEL THERAPY FOR MYC-DRIVEN MEDULLOBLASTOMA
    Ji, Pengxiang
    Genovesi, Laura
    He, Yaowu
    Hooper, John
    Wainwright, Brandon
    NEURO-ONCOLOGY, 2016, 18 : 110 - 110
  • [3] TARGETING GLUTAMINE METABOLISM AS A THERAPEUTIC STRATEGY IN MYC-DRIVEN MEDULLOBLASTOMA
    Hanaford, Allison
    Eberhart, Charles
    Archer, Tenley
    Tamayo, Pablo
    Pomeroy, Scott
    Raabe, Eric
    NEURO-ONCOLOGY, 2014, 16 : 94 - 94
  • [4] Targeting glutamine metabolism as a therapeutic strategy in MYC-driven medulloblastoma
    Hanaford, Allison Rose
    Eberhart, Charles G.
    Raabe, Eric H.
    CANCER RESEARCH, 2014, 74 (19)
  • [5] DUAL TARGETING OF PROCESSIVE TRANSCRIPTION FOR MYC-DRIVEN CIRCUITRY IN MEDULLOBLASTOMA
    Walker, Faye M.
    Madhavan, Krishna
    Sobral, Lays Martin
    Donthula, Sahiti
    Balakrishnan, Ilango
    Wang, Dong
    Pierce, Angela
    Veo, Bethany
    Karam, Sana D.
    Serkova, Natalie J.
    Foreman, Nicholas K.
    Venkataraman, Sujatha
    Vibhakar, Rajeev
    Dahl, Nathan A.
    NEURO-ONCOLOGY, 2024, 26
  • [6] Enhanced therapy for MYC-driven medulloblastoma by targeting protein translation pathway
    Chaturvedi, Nagendra K.
    Coulter, Don W.
    Kling, Matthew J.
    Ray, Sutapa
    McGuire, Timothy R.
    Joshi, Shantaram S.
    Sharp, J. Graham
    CANCER RESEARCH, 2018, 78 (13)
  • [7] An Animal Model of MYC-Driven Medulloblastoma
    Pei, Yanxin
    Moore, Colin E.
    Wang, Jun
    Tewari, Alok K.
    Eroshkin, Alexey
    Cho, Yoon-Jae
    Witt, Hendrik
    Korshunov, Andrey
    Read, Tracy-Ann
    Sun, Julia L.
    Schmitt, Earlene M.
    Miller, C. Ryan
    Buckley, Anne F.
    McLendon, Roger E.
    Westbrook, Thomas F.
    Northcott, Paul A.
    Taylor, Michael D.
    Pfister, Stefan M.
    Febbo, Phillip G.
    Wechsler-Reya, Robert J.
    CANCER CELL, 2012, 21 (02) : 155 - 167
  • [8] SYNERGISTIC TARGETING OF CDK8 AND MTOR FOR MYC-DRIVEN MEDULLOBLASTOMA
    Wang, Dong
    Ritz, Caitlin
    Luo, Yuhuan
    Veo, Bethany
    Pierce, Angela
    Vibhakar, Rajeev
    NEURO-ONCOLOGY, 2024, 26
  • [9] Targeting Myc-driven stress addiction in colorectal cancer
    Saeed, Haris
    Leibowitz, Brian J.
    Zhang, Lin
    Yu, Jian
    DRUG RESISTANCE UPDATES, 2023, 69
  • [10] Targeting MYC-driven translation
    Sarah Crunkhorn
    Nature Reviews Drug Discovery, 2017, 16 (7) : 456 - 456
12345