Analytical Platform for Monitoring Aggregation of Monoclonal Antibody Therapeutics

被引：0
|
作者：
Rohit Bansal
Surbhi Gupta
Anurag S. Rathore
机构：
[1] Indian Institute of Technology,Department of Chemical Engineering, DBT Center of Excellence for Biopharmaceutical Technology
[2] Delhi,undefined
来源：
Pharmaceutical Research | 2019年 / 36卷
关键词：
monoclonal antibody (mAb); protein aggregation; analytical characterization; size exclusion chromatography (SEC); dynamic light scattering (DLS); micro flow imaging (MFI); sub-visible particles;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Analytical Platform for Monitoring Aggregation of Monoclonal Antibody Therapeutics
    Bansal, Rohit
    Gupta, Surbhi
    Rathore, Anurag S.
    [J]. PHARMACEUTICAL RESEARCH, 2019, 36 (11)
  • [2] Circular Dichroism Spectroscopy as a Tool for Monitoring Aggregation in Monoclonal Antibody Therapeutics
    Joshi, Varsha
    Shivach, Tarun
    Yadav, Nitin
    Rathore, Anurag S.
    [J]. ANALYTICAL CHEMISTRY, 2014, 86 (23) : 11606 - 11613
  • [3] Analytical artifacts in characterization of recombinant monoclonal antibody therapeutics
    Wang, Dongdong
    Nowak, Christine
    Mason, Bruce
    Katiyar, Amit
    Liu, Hongcheng
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 183
  • [4] Analytical comparability study of recombinant monoclonal antibody therapeutics
    Ambrogelly, Alexandre
    Gozo, Stephen
    Katiyar, Amit
    Dellatore, Shara
    Kune, Yune
    Bhat, Ram
    Sun, Joanne
    Li, Ning
    Wang, Dongdong
    Nowak, Christine
    Neill, Alyssa
    Ponniah, Gomathinayagam
    King, Cory
    Mason, Bruce
    Beck, Alain
    Liu, Hongcheng
    [J]. MABS, 2018, 10 (04) : 513 - 538
  • [5] Aggregation kinetics for IgG1-based monoclonal antibody therapeutics
    Bansal, Rohit
    Singla, Akshi
    Joshi, Varsha
    Rathore, Anurag
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [6] Aggregation Kinetics for IgG1-Based Monoclonal Antibody Therapeutics
    A. Singla
    R. Bansal
    Varsha Joshi
    Anurag S. Rathore
    [J]. The AAPS Journal, 2016, 18 : 689 - 702
  • [7] Integrated Process Analytical Platform for Automated Monitoring of Monoclonal Antibody N-Linked Glycosylation
    Gyorgypal, Aron
    Chundawat, Shishir P. S.
    [J]. ANALYTICAL CHEMISTRY, 2022, 94 (19) : 6986 - 6995
  • [8] Aggregation Kinetics for IgG1-Based Monoclonal Antibody Therapeutics
    Singla, A.
    Bansal, R.
    Joshi, Varsha
    Rathore, Anurag S.
    [J]. AAPS JOURNAL, 2016, 18 (03): : 689 - 702
  • [9] Non-protein A purification platform for continuous processing of monoclonal antibody therapeutics
    Kateja, Nikhil
    Kumar, Devashish
    Sethi, Suruchi
    Rathore, Anurag S.
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2018, 1579 : 60 - 72
  • [10] Non-protein A purification platform for continuous processing of monoclonal antibody therapeutics
    Rathore, Anurag
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
12345