CBC–ARS2 stimulates 3′-end maturation of multiple RNA families and favors cap-proximal processing

被引：0

作者：

Marie Hallais

Frédéric Pontvianne

Peter Refsing Andersen

Marcello Clerici

Daniela Lener

Nour El Houda Benbahouche

Thierry Gostan

Franck Vandermoere

Marie-Cécile Robert

Stephen Cusack

Céline Verheggen

Torben Heick Jensen

Edouard Bertrand

机构：

[1] Equipe labellisée Ligue contre le Cancer,Department of Molecular Biology and Genetics

[2] Institut de Génétique Moléculaire de Montpellier–Centre National de la Recherche Scientifique,undefined

[3] Centre for mRNP Biogenesis and Metabolism,undefined

[4] Aarhus University,undefined

[5] European Molecular Biology Laboratory Grenoble Outstation,undefined

[6] Institut de Génomique Fonctionnelle,undefined

[7] Centre National de la Recherche Scientifique,undefined

[8] Present addresses: Laboratoire Génome et Développement des Plantes,undefined

[9] Centre National de la Recherche Scientifique,undefined

[10] Perpignan,undefined

[11] France (F.P.) and Institut de Génétique et de Biologie Moléculaire et Cellulaire–Centre National de la Recherche Scientifique,undefined

[12] Strasbourg,undefined

[13] France (D.L.).,undefined

来源：

Nature Structural & Molecular Biology | 2013年 / 20卷

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摘要：

The nuclear cap–binding complex (CBC) stimulates RNA maturation, but the mechanistic basis is not well understood. In vitro reconstitution experiments combined with functional analyses have revealed a new CBC complex containing ARS2, a major effector of CBC. ARS2 links the cap to 3'-end maturation for several RNA families, thus favoring the production of short RNAs.

引用

页码：1358 / 1366

页数：8

共 3 条

[1] CBC-ARS2 stimulates 3′-end maturation of multiple RNA families and favors cap-proximal processing
Hallais, Marie
Pontvianne, Frederic
Andersen, Peter Refsing
Clerici, Marcello
Lener, Daniela
Benbahouche, Nour El Houda
Gostan, Thierry
Vandermoere, Franck
Robert, Marie-Cecile
Cusack, Stephen
Verheggen, Celine
Jensen, Torben Heick
Bertrand, Edouard
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2013, 20 (12) : 1358 - 1366
[2] ARS2 Regulates Nuclear Paraspeckle Formation through 3′-End Processing and Stability of NEAT1 Long Noncoding RNA
Machitani, Mitsuhiro
Taniguchi, Ichiro
Ohno, Mutsuhito
MOLECULAR AND CELLULAR BIOLOGY, 2020, 40 (04)
[3] 3' END PROCESSING OF PRE-U2 RNA REQUIRES AN INTERACTION BETWEEN THE 3' EXTENSION AND NUCLEOTIDES IMMEDIATELY PROXIMAL TO STEM-LOOP-III
JACOBSEN, MR
PEDERSON, T
JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, : 134 - 134

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