RECIST — learning from the past to build the future

被引：0
|
作者：
Saskia Litière
Sandra Collette
Elisabeth G. E. de Vries
Lesley Seymour
Jan Bogaerts
机构：
[1] Saskia Litière,Elisabeth G. E. de Vries is at the Department of Medical Oncology
[2] Sandra Collette and Jan Bogaerts are at the EORTC Headquarters,undefined
[3] Avenue E Mounier 83/11,undefined
[4] 1200 Brussels,undefined
[5] Belgium.,undefined
[6] University Medical Center Groningen,undefined
[7] Hanzeplein,undefined
[8] 19713 GZ Groningen,undefined
[9] The Netherlands.,undefined
[10] Lesley Seymour is at the Canadian Cancer Trials Group,undefined
[11] Queen's University,undefined
[12] 10 Stuart Street,undefined
[13] Kingston,undefined
[14] Ontario K7L 3N6,undefined
[15] Canada.,undefined
来源：
Nature Reviews Clinical Oncology | 2017年 / 14卷
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摘要：
Assessment of tumour burden has become an integral part of most oncology clinical trials, and enables the evaluation of the activity and efficacy of new cancer therapeutics in solid tumours. Although RECIST was developed to assess treatment activity in early phase II trials with tumour response as the primary end point, it is now applied across the spectrum from early phase I trials through to confirmatory phase III trials. Several questions regarding the role of RECIST in the rapidly changing landscape of oncology therapeutics, and the challenges faced in its evaluation, are highlighted.
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页码：187 / 192
页数：5
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