Imaging outcomes for neuroprotection and repair in multiple sclerosis trials

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作者
Frederik Barkhof
Peter A. Calabresi
David H. Miller
Stephen C. Reingold
机构
[1] VU University Medical Center,Department of Radiology and Amsterdam MS Center
[2] Johns Hopkins School of Medicine,Department of Neurology
[3] Institute of Neurology,Department of Neuroinflammation and NMR Research Unit
[4] University College London,undefined
[5] National MS Society and Scientific and Clinical Review Associates,undefined
[6] LLC,undefined
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摘要
Multiple sclerosis is traditionally considered to be an inflammatory disease, but it also has a neurodegenerative component, which can manifest early in the disease course. New therapeutic strategies are being developed to elicit CNS neuroprotection and repair in patients with multiple sclerosis, and Barkhof et al. review the available data on imaging outcome measures that could be used to track the efficacy of these approaches.
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页码:256 / 266
页数:10
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