CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors

被引：0

作者：

Lokesh A Kalekar

Shirdi E Schmiel

Sarada L Nandiwada

Wing Y Lam

Laura O Barsness

Na Zhang

Gretta L Stritesky

Deepali Malhotra

Kristen E Pauken

Jonathan L Linehan

M Gerard O'Sullivan

Brian T Fife

Kristin A Hogquist

Marc K Jenkins

Daniel L Mueller

机构：

[1] University of Minnesota Medical School,Department of Medicine

[2] The Center for Immunology,Department of Laboratory Medicine and Pathology

[3] University of Minnesota Medical School,Department of Microbiology

[4] University of Minnesota Medical School,undefined

[5] University of Minnesota Medical School,undefined

[6] The Comparative Pathology Core at the Masonic Cancer Center,undefined

[7] University of Minnesota Medical School,undefined

来源：

Nature Immunology | 2016年 / 17卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

T cell anergy is a well-established phenomenon, but its physiological role is unclear. Mueller and colleagues demonstrate that anergic self-reactive T cells are present at steady state and that these are predisposed to generate peripheral regulatory T cells.

引用

页码：304 / 314

页数：10

共 50 条

[1] CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
Kalekar, Lokesh A.
Schmiel, Shirdi E.
Nandiwada, Sarada L.
Lam, Wing Y.
Barsness, Laura O.
Zhang, Na
Stritesky, Gretta L.
Malhotra, Deepali
Pauken, Kristen E.
Linehan, Jonathan L.
O'Sullivan, M. Gerard
Fife, Brian T.
Hogquist, Kristin A.
Jenkins, Marc K.
Mueller, Daniel L.
[J]. NATURE IMMUNOLOGY, 2016, 17 (03) : 304 - 314
[2] Regulatory CD4+ T Cells Promote B Cell Anergy in Murine Lupus
Liu, Yaoyang
Liu, Aijing
Iikuni, Noriko
Xu, Huji
Shi, Fu-Dong
La Cava, Antonio
[J]. JOURNAL OF IMMUNOLOGY, 2014, 192 (09): : 4069 - 4073
[3] Molecular mechanisms of CD4+ T-cell anergy
Fathman, C. Garrison
Lineberry, Neil B.
[J]. NATURE REVIEWS IMMUNOLOGY, 2007, 7 (08) : 599 - 609
[4] Molecular mechanisms of CD4+ T-cell anergy
C. Garrison Fathman
Neil B. Lineberry
[J]. Nature Reviews Immunology, 2007, 7 : 599 - 609
[5] CD4+ T-cell subsets in autoimmunity
O'Garra, A
Steinman, L
Gijbels, K
[J]. CURRENT OPINION IN IMMUNOLOGY, 1997, 9 (06) : 872 - 883
[6] Antigen-driven CD4+ T-cell anergy: a pathway to peripheral T regulatory cells
Eggenhuizen, Peter J.
Ng, Boaz H.
Ooi, Joshua D.
[J]. IMMUNOLOGY AND CELL BIOLOGY, 2021, 99 (03): : 252 - 254
[7] CD4+ regulatory T cell responses induced by T cell vaccination
Zhang, J.
[J]. CURRENT TOPICS IN NEUROIMMUNOLOGY, 2006, : 77 - 83
[8] Identifying memory CD4+ T cell precursors
Yvonne Bordon
[J]. Nature Reviews Immunology, 2011, 11 (12) : 803 - 803
[9] Regulatory CD4+ T cells are crucial for preventing CD8+ T cell-mediated autoimmunity
Poitrasson-Riviere, Maud
Bienvenu, Boris
Le Campion, Armelle
Becourt, Chantal
Martin, Bruno
Lucas, Bruno
[J]. JOURNAL OF IMMUNOLOGY, 2008, 180 (11): : 7294 - 7304
[10] CD4+ regulatory T cells in autoimmunity and allergy
de Lafaille, MAC
Lafaille, JJ
[J]. CURRENT OPINION IN IMMUNOLOGY, 2002, 14 (06) : 771 - 778

← 1 2 3 4 5 →