Synthesis and properties of 6,6-di(indol-3-yl)-indolo[2,1-b]quinazolin-12(6H)-one and its 2,8-dimethyl and 2,8-dibromo derivatives

被引：0

作者：

T. V. Moskovkina

A. I. Kalinovskii

E. A. Martyyas

M. M. Anisimov

机构：

[1] Far East State University,G. V. Elyakov Pacific Ocean Institute of Bioorganic Chemistry, Far East Branch

[2] Russian Academy of Sciences,undefined

来源：

Chemistry of Heterocyclic Compounds | 2013年 / 49卷

关键词：

indole; indolo[2,1-; ]quinazolines; antimicrobial action; condensation; fluorescence;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The condensation of tryptanthrin, as well as its 2,8-dimethyl and 2,8-dibromo derivatives with indole gave previously unreported 6,6-di(indol-3-yl)indolo[2,1-b]quinazolin-12(6H)-ones. 2,8-Disubstituted tryptanthrins and 6,6-di(indol-3-yl)indolo[2,1-b]quinazolin-12(6H)-one were shown to inhibit Candida albicans KMM 455. Solutions of tryptanthrin itself and its 6,6-diindolyl derivative upon the absorption of light at 434 and 340 nm exhibited fluorescence maxima at λmax 525 and 500 nm, respectively.

引用

页码：452 / 456

页数：4

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