Engineering synthetic vaccines using cues from natural immunity

被引：0
|
作者：
Darrell J. Irvine
Melody A. Swartz
Gregory L. Szeto
机构：
[1] Massachusetts Institute of Technology (MIT),Department of Materials Science and Engineering
[2] MIT,Department of Biological Engineering
[3] Koch Institute for Integrative Cancer Research,undefined
[4] MIT,undefined
[5] The Ragon Institute of MGH,undefined
[6] MIT,undefined
[7] and Harvard,undefined
[8] Howard Hughes Medical Institute,undefined
[9] Laboratory of Lymphatic and Cancer Bioengineering,undefined
[10] Institute of Bioengineering and Swiss Institute for Experimental Cancer Research (ISREC),undefined
[11] École Polytechnique Fédérale de Lausanne (EPFL),undefined
来源：
Nature Materials | 2013年 / 12卷
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学科分类号：
摘要：
The clinical application of vaccines has expanded from infectious diseases to cancer, enhancing our vision of how the immune system can be used to prevent and treat disease. This Review highlights recent developments, clinical successes and future challenges in the design of prophylactic, therapeutic and tolerance-inducing synthetic vaccines with inspiration from the natural immune system.
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页码：978 / 990
页数：12
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