Recent advances, approaches and challenges in targeting pathways for potential COVID-19 vaccines development

被引：0
|
作者：
Daniela Calina
Chandan Sarkar
Andreea Letitia Arsene
Bahare Salehi
Anca Oana Docea
Milon Mondal
Muhammad Torequl Islam
Alireza Zali
Javad Sharifi-Rad
机构：
[1] University of Medicine and Pharmacy of Craiova,Department of Clinical Pharmacy
[2] Bangabandhu Sheikh Mujibur Rahman Science and Technology University,Department of Pharmacy
[3] Carol Davila University of Medicine and Pharmacy,Department of Department of Microbiology
[4] Bam University of Medical Sciences,Noncommunicable Diseases Research Center
[5] Bam University of Medical Sciences,Student Research Committee, School of Medicine
[6] University of Medicine and Pharmacy of Craiova,Department of Toxicology
[7] Shahid Beheshti University of Medical Sciences,Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Comprehensive Center of Excellence
[8] Shahid Beheshti University of Medical Sciences,Phytochemistry Research Center
来源：
Immunologic Research | 2020年 / 68卷
关键词：
SARS-CoV-2; COVID-19 pandemic ; Immunology ; Candidate vaccines; Safety ; Efficacy ; Quality ; Public health;
D O I：
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中图分类号：
学科分类号：
摘要：
During the COVID-19 pandemic in a modern era, there is a global consensus on the need for the rapid development of a vaccine against SARS-CoV-2 for effective and sustainable control. Developing these vaccines is fundamental to public health. This urgent need is supported by the scientific explosion in structural and genomic biology that facilitates the urgent development of an ideal COVID-19 vaccine, using new pathways to facilitate its large-scale development, testing, and manufacture. Here, we summarize the types of COVID-19 candidate vaccines, their current stage in early testing in human clinical trials, and the challenges for their implementation.
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页码：315 / 324
页数：9
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