The role of urokinase in cell migration induced by growth factors

被引：0
|
作者：
V. V. Stepanova
A. Bobik
S. P. Domogatskii
S. A. Mukhina
V. A. Tkachuk
机构：
[1] Ministry of Health,Laboratory of Molecular Endocrinology, Russian Cardiology Research
[2] Ministry of Health,and
[3] Baker Medical Research Institute,Production Complex
[4] M. V. Lomonosov Moscow State University,Laboratory of Engineering Immunology, Russian Cardiology Research
来源：
Bulletin of Experimental Biology and Medicine | 1999年 / 127卷
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摘要：
The role of urokinase (serine protease converting plasminogen into plasmin) and its receptor in cell migration was studied on cultured smooth muscle cells from rat aorta. Platelet-derived growth factor, fibroblast growth factor-2, and urokinase activated migration of smooth muscle cells. Antibodies against urokinase inhibited cell migration induced by both urokinase and other growth factors. It is assumed that urokinase is involved in vascular remodeling induced by growth factors.
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页码：256 / 258
页数：2
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