Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

被引：0

作者：

Jenny M Mjösberg

Sara Trifari

Natasha K Crellin

Charlotte P Peters

Cornelis M van Drunen

Berber Piet

Wytske J Fokkens

Tom Cupedo

Hergen Spits

机构：

[1] Tytgat Institute for Liver and Intestinal Research,Department of Immunology

[2] University of Amsterdam,Department of Otorhinolaryngology

[3] Genentech,Department of Experimental Immunology and Pulmonology of the Academic Medical Center

[4] University of Amsterdam,Department of Hematology

[5] University of Amsterdam,undefined

[6] Erasmus University Medical Center,undefined

[7] Present address: La Jolla Institute for Allergy and Immunology,undefined

[8] La Jolla,undefined

[9] California,undefined

[10] USA (S.T.),undefined

[11] and Pfizer at Rinat,undefined

[12] San Francisco,undefined

[13] California,undefined

[14] USA (N.K.C.).,undefined

来源：

Nature Immunology | 2011年 / 12卷

关键词：

D O I：

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学科分类号：

摘要：

Mice have lineage-negative IL-7Rα+ (innate lymphoid) cells that contribute to type 2 immunity. Spits and colleagues identify a similar CRTH2+CD161+ population in human lungs and gut that produces IL-13 after stimulation.

引用

页码：1055 / 1062

页数：7

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