Big Bang and context-driven collapse

被引：0

作者：

Mark Robertson-Tessi

Alexander R A Anderson

机构：

[1] H. Lee Moffitt Cancer Center and Research Institute,Mark Robertson

[2] Tampa,Tessi and Alexander R. A. Anderson are in the Integrated Mathematical Oncology Department

[3] Florida,undefined

[4] USA.,undefined

来源：

Nature Genetics | 2015年 / 47卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Heterogeneity is the single most important factor driving cancer progression and treatment failure, yet little is understood about how and when this heterogeneity arises. A new study shows that colorectal cancers acquire their dominant mutations early in development and that subsequent mutations, even if they confer greater fitness, are unlikely to sweep through the tumor.

引用

页码：196 / 197

页数：1

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