1. The noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists produce behavioral responses that closely resemble both positive and negative symptoms of schizophrenia. These drugs also induce excitatory and neurotoxic effects in limbic cortical areas.
机构:
UNIV CAMBRIDGE,PARKE DAVIS NEUROSCI RES CTR,FORVIE SITE,CAMBRIDGE CB2 2QB,ENGLANDUNIV CAMBRIDGE,PARKE DAVIS NEUROSCI RES CTR,FORVIE SITE,CAMBRIDGE CB2 2QB,ENGLAND
Panegyres, PK
Hughes, J
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机构:
UNIV CAMBRIDGE,PARKE DAVIS NEUROSCI RES CTR,FORVIE SITE,CAMBRIDGE CB2 2QB,ENGLANDUNIV CAMBRIDGE,PARKE DAVIS NEUROSCI RES CTR,FORVIE SITE,CAMBRIDGE CB2 2QB,ENGLAND