Graft-versus-tumor effect in a patient with advanced neuroblastoma who received HLA haplo-identical bone marrow transplantation

被引：0
|
作者：
M Inoue
T Nakano
A Yoneda
M Nishikawa
M Nakayama
K Yumura-Yagi
N Sakata
M Yasui
T Okamura
K Kawa
机构：
[1] Osaka Medical Center and Research Institute for Maternal and Child Health,Department of Pediatrics
[2] Nara Medical University,Department of Pediatrics
[3] Osaka University Graduate School of Medicine,Department of Pediatric Surgery
[4] Osaka Medical Center and Research Institute for Maternal and Child Health,Department of Radiology
[5] Osaka Medical Center and Research Institute for Maternal and Child Health,Department of Pathology
来源：
Bone Marrow Transplantation | 2003年 / 32卷
关键词：
neuroblastoma; CD34; graft-versus-tumor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A 5-year-old boy received CD34-positive HLA haplo-identical bone marrow transplantation from his father as treatment for refractory advanced neuroblastoma. He had residual disease in the para-aortic lymph nodes and multiple bones after the transplant. However, all of his residual disease had disappeared completely 3 years later. He developed grade I acute graft-versus-host disease (GVHD) but had no symptoms of chronic GVHD or any other complications. This case demonstrates the possibility of a graft-versus-tumor effect against neuroblastoma by HLA-mismatched allogeneic hematopoietic stem cell transplantation.
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页码：103 / 106
页数：3
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