Obesity and cardiovascular risk

被引：0
|
作者：
Karuparthi P.R. [1 ]
Yerram P. [1 ]
Govindarajan G. [1 ]
Hayden M.R. [1 ]
机构：
[1] Department of Internal Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Missouri-Columbia School of Medicine, Health Sciences Center, Columbia, MO, 65212, MA410, DC043.0, One Hospital Drive
来源：
Current Cardiovascular Risk Reports | 2008年 / 2卷 / 2期
基金：
加拿大创新基金会; 加拿大健康研究院;
关键词：
Obesity; Insulin Resistance; Adipose Tissue; White Adipose Tissue; Visceral Adipose Tissue;
D O I：
10.1007/s12170-008-0022-3
中图分类号：
学科分类号：
摘要：
Obesity has assumed epidemic proportions and is expected to decrease the life expectancy of current and future generations by its cardiovascular complications and other associated chronic diseases. Recognizing the gravity of this trend, the American Heart Association recently identified obesity as an independent and important modifiable risk factor for cardiovascular disease. Obesity is known to cluster with other cardiovascular and metabolic risk factors constituting the cardiometabolic syndrome. The pathophysiogic link between obesity and cardiovascular disease is complex and involves multiple metabolic and inflammatory risk factors. In an attempt to better elucidate this major public health problem, this article reviews obesity as an epidemic, the structural and functional changes in the cardiovascular system as a result of obesity, and the pathophysiology of obesity-related cardiomyopathy. The sheer magnitude of the problem of obesity with its immense cardiovascular consequences warrants immediate intervention. © 2008 Current Medicine Group LLC.
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页码：113 / 119
页数：6
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