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- [1] Therapeutic effect of dual CAR-T targeting PDL1 and MUC16 antigens on ovarian cancer cells in miceBMC CANCER, 2020, 20 (01)Li, Tong论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Gynecol Oncol, Beijing 100006, Peoples R China Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Gynecol Oncol, Beijing 100006, Peoples R ChinaWang, Jiandong论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Gynecol Oncol, Beijing 100006, Peoples R China Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Gynecol Oncol, Beijing 100006, Peoples R China
- [2] Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023, 72 (11) : 3773 - 3786Mun, Sung Soo论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAMeyerberg, Jeremy论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAPeraro, Leila论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAKorontsvit, Tatyana论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAGardner, Thomas论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAMalviya, Manish论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAKyi, Chrisann论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA Weill Cornell Med Coll, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAO'Cearbhaill, Roisin E.论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA Weill Cornell Med Coll, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USALiu, Cheng论文数: 0 引用数: 0 h-index: 0机构: Eureka Therapeut Inc, Emeryville, CA USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USADao, Tao论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USAScheinberg, David A.论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA Weill Cornell Med Coll, New York, NY 10065 USA Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, 1275 York Ave, New York, NY 10065 USA
- [3] Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1Cancer Immunology, Immunotherapy, 2023, 72 : 3773 - 3786Sung Soo Mun论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramJeremy Meyerberg论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramLeila Peraro论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramTatyana Korontsvit论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramThomas Gardner论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramManish Malviya论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramChrisann Kyi论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramRoisin E. O’Cearbhaill论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramCheng Liu论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramTao Dao论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology ProgramDavid A. Scheinberg论文数: 0 引用数: 0 h-index: 0机构: Memorial Sloan Kettering Cancer Center,Molecular Pharmacology Program
- [4] Novel mesothelin-based CAR T cells targeting MUC16 as an intravesical bladder cancer therapyCLINICAL CANCER RESEARCH, 2024, 30 (10)Abrahimi, Parwiz论文数: 0 引用数: 0 h-index: 0Khan, Jonathan论文数: 0 引用数: 0 h-index: 0Brentjens, Renier论文数: 0 引用数: 0 h-index: 0Merghoub, Taha论文数: 0 引用数: 0 h-index: 0Wolchok, Jedd论文数: 0 引用数: 0 h-index: 0
- [5] INTRAVESICAL MUC16 TARGETING CAR T CELLS FOR ORGAN-CONFINED BLADDER CANCERSUROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2025, 43 (03)Parwiz, Abrahimi论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAJonathan, Khan论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAAlyssa, Duren-Lubanski论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAWinson, Cai论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAYacine, Marouf论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAJacob, Tallman论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USABishoy, Faltas论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAHikmat, Al Ahmadie论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAOlivier, Elemento论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USABenjamin, Hopkins论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USADouglas, Scherr论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USARenier, Brentjens论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USAJedd, Wolchok论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USATaha, Merghoub论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Urol, New York, NY USA Weill Cornell Urol, New York, NY USA
- [6] Enhancing the antitumor effect of MUC16 CART cells in ovarian cancer: The potential of oncolytic adenovirusCANCER LETTERS, 2025, 616Wang, Qiuman论文数: 0 引用数: 0 h-index: 0机构: Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaLiu, Wanchuan论文数: 0 引用数: 0 h-index: 0机构: Hebei Med Univ, Hosp 4, Dept Reprod Med, Shijiazhuang 050011, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaFan, Yuanchun论文数: 0 引用数: 0 h-index: 0机构: Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaLiu, Shihao论文数: 0 引用数: 0 h-index: 0机构: Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaLi, Rongrong论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Qilu Hosp, Dept Obstet & Gynecol, Jinan 250012, Peoples R China Shandong Univ, Qilu Hosp, Shandong Key Lab Reprod Hlth & Birth Defects Preve, Jinan 250012, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaYan, Shi论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Qilu Hosp, Dept Obstet & Gynecol, Jinan 250012, Peoples R China Shandong Univ, Qilu Hosp, Shandong Key Lab Reprod Hlth & Birth Defects Preve, Jinan 250012, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaSong, Kun论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Qilu Hosp, Dept Obstet & Gynecol, Jinan 250012, Peoples R China Shandong Univ, Qilu Hosp, Shandong Key Lab Reprod Hlth & Birth Defects Preve, Jinan 250012, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaZhang, Hui论文数: 0 引用数: 0 h-index: 0机构: Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R ChinaYuan, Cunzhong论文数: 0 引用数: 0 h-index: 0机构: Shandong Univ, Qilu Hosp, Dept Obstet & Gynecol, Jinan 250012, Peoples R China Shandong Univ, Qilu Hosp, Shandong Key Lab Reprod Hlth & Birth Defects Preve, Jinan 250012, Peoples R China Hebei Med Univ, Hosp 4, Dept Gynecol, Shijiazhuang 050011, Peoples R China
- [7] EPIDEMIOLOGIC AND MEDICAL FACTORS ASSOCIATED WITH ANTIBODIES AGAINST TUMOR ASSOCIATED ANTIGENS MUC1 AND MUC16: POSSIBLE RELEVANCE TO OVARIAN CANCERAMERICAN JOURNAL OF EPIDEMIOLOGY, 2013, 177 : S89 - S89Williams, Kristina论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USAVitonis, Allison论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USAYamamoto, Hidemi论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USAFichorova, Raina N.论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USACramer, Daniel论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Brigham & Womens Hosp, OB GYN Epidemiol Ctr, Boston, MA 02115 USA
- [8] Tandem CAR-T cells targeting FOLR1 and MSLN enhance the antitumor effects in ovarian cancerINTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 17 (15): : 4365 - 4376Liang, Zhen论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaDong, Jiao论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Guangyuan Tradit Chinese Med Hosp, Dept Obstet & Gynecol, Guangyuan, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaYang, Neng论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaLi, Si-Di论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaYang, Ze-Yu论文数: 0 引用数: 0 h-index: 0机构: Univ Chinese Acad Sci, Chongqing Gen Hosp, Breast & Thyroid Surg Dept, Chongqing, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaHuang, Rui论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Inst Pathol & Southwest Canc Ctr, Army Med Univ, Chongqing, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaLi, Feng-Jie论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaWang, Wen-Ting论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaRen, Jia-Kui论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaLei, Jie论文数: 0 引用数: 0 h-index: 0机构: Hui Long Ba Town Hosp, Dept Internal Med, Chongqing, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaXu, Chen论文数: 0 引用数: 0 h-index: 0机构: Fourth Mil Med Univ, Xijing Hosp, Dept Hepatobiliary Surg, Xian, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaWang, Dan论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaWang, Yan-Zhou论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R ChinaLiang, Zhi-Qing论文数: 0 引用数: 0 h-index: 0机构: Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China Third Mil Med Univ, Southwest Hosp, Dept Obstet & Gynecol, Army Med Univ, 30 Gaotanyan Main St, Chongqing 400038, Peoples R China
- [9] ROR1-targeting switchable CAR-T cells for cancer therapyOncogene, 2022, 41 : 4104 - 4114Haiyong Peng论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchThomas Nerreter论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchKatrin Mestermann论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchJakob Wachter论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchJing Chang论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchMichael Hudecek论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical ResearchChristoph Rader论文数: 0 引用数: 0 h-index: 0机构: University of Florida,Department of Immunology and Microbiology, UF Scripps Biomedical Research
- [10] ROR1-targeting switchable CAR-T cells for cancer therapyONCOGENE, 2022,Peng, Haiyong论文数: 0 引用数: 0 h-index: 0机构: Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USA Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USANerreter, Thomas论文数: 0 引用数: 0 h-index: 0机构: Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USAMestermann, Katrin论文数: 0 引用数: 0 h-index: 0机构: Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USAWachter, Jakob论文数: 0 引用数: 0 h-index: 0机构: Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USAChang, Jing论文数: 0 引用数: 0 h-index: 0机构: Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USA Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USAHudecek, Michael论文数: 0 引用数: 0 h-index: 0机构: Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USARader, Christoph论文数: 0 引用数: 0 h-index: 0机构: Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USA Univ Florida, Dept Immunol & Microbiol, Scripps Biomed Res, Jupiter, FL 33458 USA