In Vitro Studies of Intestinal Permeability and Hepatic and Intestinal Metabolism of 8-Prenylnaringenin, a Potent Phytoestrogen from Hops (Humulus lupulus L.)

被引：0
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作者：
Dejan Nikolic
Yongmei Li
Lucas R. Chadwick
Richard B. van Breemen
机构：
[1] University of Illinois at Chicago,Department of Medicinal Chemistry and Pharmacognosy, UIC/NIH Center for Botanical Dietary Supplements Research, College of Pharmacy
来源：
Pharmaceutical Research | 2006年 / 23卷
关键词：
Caco-2 cells; hops; liquid chromatography–mass spectrometry (LC–MS); metabolism; natural products; 8-prenylnaringenin;
D O I：
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学科分类号：
摘要：
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页码：864 / 872
页数：8
相关论文
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  • [1] In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.)
    Nikolic, Dejan
    Li, Yongmei
    Chadwick, Lucas R.
    van Breemen, Richard B.
    [J]. PHARMACEUTICAL RESEARCH, 2006, 23 (05) : 864 - 872
  • [2] Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes
    Nikolic, D
    Li, YM
    Chadwick, LR
    Grubjesic, S
    Schwab, P
    Metz, P
    van Breemen, RB
    [J]. DRUG METABOLISM AND DISPOSITION, 2004, 32 (02) : 272 - 279
  • [3] The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine
    Possemiers, Sam
    Bolca, Selin
    Grootaert, Charlotte
    Heyerick, Arne
    Decroos, Karel
    Dhooge, Willem
    De Keukeleire, Denis
    Rabot, Sylvie
    Verstraete, Willy
    Van de Wiele, Tom
    [J]. JOURNAL OF NUTRITION, 2006, 136 (07): : 1862 - 1867
  • [4] Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine
    Possemiers, Sam
    Rabot, Sylvie
    Espin, Juan Carlos
    Bruneau, Aurelia
    Philippe, Catherine
    Gonzalez-Sarrias, Antonio
    Heyerick, Arne
    Tomas-Barberan, Francisco A.
    De Keukeleire, Denis
    Verstraete, Willy
    [J]. JOURNAL OF NUTRITION, 2008, 138 (07): : 1310 - 1316
  • [5] Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota;: Conversion of isoxanthohumol into 8-prenylnaringenin
    Possemiers, S
    Heyerick, A
    Robbens, V
    De Keukeleire, D
    Verstraete, W
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (16) : 6281 - 6288
  • [6] Therapeutic Perspectives of 8-Prenylnaringenin, a Potent Phytoestrogen from Hops
    Stulikova, Katerina
    Karabin, Marcel
    Nespor, Jakub
    Dostalek, Pavel
    [J]. MOLECULES, 2018, 23 (03):
  • [7] Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.)
    Guo, Jian
    Nikolic, Dejan
    Chadwick, Lucas R.
    Pauli, Guido F.
    van Breemen, Richard B.
    [J]. DRUG METABOLISM AND DISPOSITION, 2006, 34 (07) : 1152 - 1159
  • [8] Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer.
    Milligan, SR
    Kalita, JC
    Heyerick, A
    Rong, H
    De Cooman, L
    De Keukeleire, D
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (06): : 2249 - 2252
  • [9] Quantitation of 8-prenylnaringenin, a novel phytoestrogen in hops (Humulus lupulus L.), hop products, and beers, by benchtop HPLC-MS using electrospray ionization
    H. Rong
    Y. Zhao
    K. Lazou
    D. De Keukeleire
    S. R. Milligan
    P. Sandra
    [J]. Chromatographia, 2000, 51 : 545 - 552
  • [10] Potent phyto-oestrogenicity of 8-prenylnaringenin and cancer-chemopreventive activity of xanthohumol, prenylated flavonoids derived from hops (Humulus lupulus L.)
    不详
    [J]. EJC SUPPLEMENTS, 2004, 2 (09): : 109 - 109
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