Saturable Absorptive Transport of the Hydrophilic Organic Cation Ranitidine in Caco-2 Cells: Role of pH-Dependent Organic Cation Uptake System and P-Glycoprotein

被引：0
|
作者：
David L. Bourdet
Dhiren R. Thakker
机构：
[1] The University of North Carolina at Chapel Hill,Division of Molecular Pharmaceutics, School of Pharmacy, Kerr Hall, CB #7360
来源：
Pharmaceutical Research | 2006年 / 23卷
关键词：
carrier-mediated transport; intestinal absorption; organic cation transport; P-glycoprotein; ranitidine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1165 / 1177
页数：12
相关论文
共 50 条
  • [1] Saturable absorptive transport of the hydrophilic organic cation ranitidine in caco-2 cells: Role of pH-Dependent organic cation uptake system and p-glycoprotein
    Bourdet, David L.
    Thakker, Dhiren R.
    [J]. PHARMACEUTICAL RESEARCH, 2006, 23 (06) : 1165 - 1177
  • [2] Intestinal absorptive transport of the hydrophilic cation ranitidine:: A kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in caco-2 cells
    Bourdet, David L.
    Pollack, Gary M.
    Thakker, Dhiren R.
    [J]. PHARMACEUTICAL RESEARCH, 2006, 23 (06) : 1178 - 1187
  • [3] Intestinal Absorptive Transport of the Hydrophilic Cation Ranitidine: A Kinetic Modeling Approach to Elucidate the Role of Uptake and Efflux Transporters and Paracellular vs. Transcellular Transport in Caco-2 Cells
    David L. Bourdet
    Gary M. Pollack
    Dhiren R. Thakker
    [J]. Pharmaceutical Research, 2006, 23 : 1178 - 1187
  • [4] Influence of extracellular glucose concentration on organic cation transport in Caco-2 cells
    Faria, Ana Isabel
    Monteiro, Rosario
    Mateus, Nuno
    Azevedo, Isabel
    Calhau, Conceicao
    [J]. FASEB JOURNAL, 2007, 21 (05): : A730 - A730
  • [5] Characterization of MPP+ secretion across human intestinal Caco-2 cell monolayers:: role of P-glycoprotein and a novel Na+-dependent organic cation transport mechanism
    Bleasby, K
    Chauhan, S
    Brown, CDA
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 2000, 129 (03) : 619 - 625
  • [6] Thiamine is a substrate of organic cation transporters in Caco-2 cells
    Lemos, Clara
    Faria, Ana
    Meireles, Manuela
    Martel, Fatima
    Monteiro, Rosario
    Calhau, Conceicao
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 682 (1-3) : 37 - 42
  • [7] Diphenhydramine transport by pH-dependent tertiary amine transport system in Caco-2 cells
    Mizuuchi, H
    Katsura, T
    Ashida, K
    Hashimoto, Y
    Inui, KI
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2000, 278 (04): : G563 - G569
  • [8] Echinacea purpurea and P-Glycoprotein Drug Transport in Caco-2 Cells
    Hansen, Torstein Schroder
    Nilsen, Odd Georg
    [J]. PHYTOTHERAPY RESEARCH, 2009, 23 (01) : 86 - 91
  • [9] Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers
    Soon-Sun Hong
    Sang-Cherl Moon
    Chang-Koo Shim
    [J]. Archives of Pharmacal Research, 2006, 29
  • [10] Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers
    Hong, SS
    Moon, SC
    Shim, CK
    [J]. ARCHIVES OF PHARMACAL RESEARCH, 2006, 29 (04) : 318 - 322
12345