Synthesis of l-Ascorbic Acid Lactone Derivatives

被引：7
|
作者：
Shao L.-D. [1 ,2 ]
Wu Y.-N. [1 ,2 ]
Xu J. [1 ,2 ]
He J. [1 ]
Zhao Y. [1 ]
Peng L.-Y. [1 ]
Li Y. [1 ]
Yang Y.-R. [1 ]
Xia C.-F. [1 ]
Zhao Q.-S. [1 ]
机构：
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming
[2] Graduate School of the Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing
来源：
Natural Products and Bioprospecting | 2014年 / 4卷 / 3期
基金：
中国国家自然科学基金;
关键词：
Cytotoxicity; Focused library; l-Ascorbic acid lactone;
D O I：
10.1007/s13659-014-0022-6
中图分类号：
学科分类号：
摘要：
A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were synthesized. Among these lactones, lactones 8–12 were new compounds. The cytotoxicity of these synthetic compounds were investigated. © 2014, The Author(s).
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页码：181 / 188
页数：7
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