Vitamin D in European children—statement from the European Academy of Paediatrics (EAP)

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作者
Zachi Grossman
Adamos Hadjipanayis
Tom Stiris
Stefano del Torso
Jean-Christophe Mercier
Arunas Valiulis
Raanan Shamir
机构
[1] Maccabi Health Services,Pediatric Clinic
[2] Larnaca General Hospital,Department of Paediatrics
[3] European University of Cyprus,School of Medicine
[4] Oslo University Hospital,Department of Neonatology
[5] University of Oslo,Faculty of Medicine
[6] Dipartimento della Sanità Pubblica,Service de Pédiatrie
[7] ULSS 6,Urgences, Hôpital Louis Mourier
[8] Assistance Publique-Hôpitaux de Paris and Université Paris Diderot,Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Medical Center
[9] Vilnius University Clinic of Children’s Diseases and Public Health Institute,undefined
[10] Tel Aviv University,undefined
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关键词
European Academy of Paediatrics; Vitamin D;
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摘要
Vitamin D is synthesized in human skin upon sun exposure and is also a nutrient. It regulates calcium and phosphate metabolism and is essential for the maintenance of bone health. Vitamin D supplementation during infancy, in order to prevent rickets, is universally accepted. Many human cell types carry vitamin D receptor, this being a drive for conducting studies on the possible association between vitamin D status and other diseases. Studies have affirmed that a considerable number of healthy European children may be vitamin D deficient, especially in high-risk groups (darker pigmented skin, living in areas with reduced sun exposure and other disorders). However, the definition of deficiency is unclear due to inter assay differences and due to a lack of consensus as to what is an “adequate” 25(OH)D level. Therefore, there is no justification for routine screening for vitamin D deficiency in healthy children. An evaluation of vitamin D status is justified in children belonging to high-risk groups. All infants up to 1 year of age should receive an oral supplementation of 400 IU/day of vitamin D. Beyond this age, seasonal variation of sunlight should be taken into account when considering a national policy of supplementation or fortification.
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页码:829 / 831
页数:2
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