Development of a liquid phase radioimmunoassay for the measurement of serum ferritin levels for the detection of Covid-19 in patients

被引：0

作者：

Emil Michael Riad

Manal Asem Emam

Nahed Hassan Ebeid

Ahmed Sami El-bayoumy

Khaled Mohamed Sallam

Nagy Lahzy Mehany

Shadia Abdel-Hamid Fathy

机构：

[1] Atomic Energy Authority,Department of Labeled Compounds, Hot labs Centre

[2] Ain Shams University,Department of Biochemistry, Faculty of Science

来源：

Journal of Radioanalytical and Nuclear Chemistry | 2022年 / 331卷

关键词：

Ferritin; Covid-19; Radioimmunoassay; Labelling; I; Tracer;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The aim of this study was the development and analytically validation of a radioimmunoassay system for the measurement of the serum ferritin concentration as one of the laboratory biomarkers for infection by Covid-19. The main components of the system were prepared in our laboratories. The first component ferritin was extracted and purified from human spleen with high purity. The second component was the 125I-labelled ferritin tracer, prepared using Chloramine-T method. Furthermore anti-ferritin antibodies and ferritin standards were provided. The developed system is sensitive, precise, reproducible and.

引用

页码：1389 / 1396

页数：7

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