RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer’s disease, and normative aging

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作者：
Helen Wong
Jordan M. Buck
Curtis Borski
Jessica T. Pafford
Bailey N. Keller
Ryan A. Milstead
Jessica L. Hanson
Jerry A. Stitzel
Charles A. Hoeffer
机构：
[1] Institute for Behavioral Genetics,Department of Integrative Physiology
[2] University of Colorado Boulder,undefined
[3] University of Colorado,undefined
[4] Linda Crnic Institute,undefined
[5] Anschutz Medical Campus,undefined
来源：
Journal of Neurodevelopmental Disorders | 2022年 / 14卷
关键词：
Down syndrome; Alzheimer’s; Calcineurin; Circadian rhythms; DSCR1; Free-running; Light-entrained; Aging;
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